Gene
il23r
- ID
- ZDB-GENE-080107-5
- Name
- interleukin 23 receptor
- Symbol
- il23r Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have cytokine receptor activity and interleukin-2 binding activity. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); inflammatory bowel disease (multiple); and psoriasis (multiple). Orthologous to human IL23R (interleukin 23 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liongue et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory bowel disease 17 | Alliance | {Inflammatory bowel disease 17, protection against} | 612261 |
| psoriasis 7 | Alliance | {Psoriasis, protection against} | 605606 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Type I Cytokine Receptor Family, Type 2 Subfamily |
|---|---|---|---|---|---|
|
UniProtKB:F8W454
|
857 | ||||
|
UniProtKB:A8WH98
|
818 |
Interactions and Pathways
No data available
Plasmids
No data available